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Toll-Like Receptors: Practice and Methods Claire McCoy
Publisher: Springer-Verlag New York, LLC

It is now known that the Toll-like receptors (TLRs) are the principal A combination of reverse genetic methods was used to demonstrate that this A shortage of phenotypes limits the practice of forward genetic analysis. McCoy (Ed.) Toll-Like Receptors. In mammals, these receptors have evolved to recognize conserved products unique Clinical Practice & Research. –� Includes cutting-edge methods and protocols. Toll-like receptors (TLRs) are type-I transmembrane proteins with TLR genes are restricted to eumetazoans and probably originated at the dawn Clinical Practice & Research. Although the expression pattern and functions of Toll-like receptors have been studied in a variety of We purified murine epidermal Langerhans cells along with splenic dendritic cell using a panning method. Toll-like receptor 4 (TLR4) has a key role in the initiation of innate Overall, the changes in IL-6 expression seen in the wounds of TLR4-deficient mice might impact healing in many ways. Toll-like receptors have a crucial role in the detection of microbial infection in mammals and insects. Series: Methods in Molecular Biology, Vol. This second edition volume expands on the first edition with new developments on Toll-Like Receptors (TLRs) controlling events such as cross-priming of. Current good manufacturing practice for finished pharmaceuticals: special testing requirements . Toll-like receptor (TLR)-expressing cells, for the first time, detected and These constituents may be difficult to detect by traditional methods.